LRI Toolbox


Over the past 12 years the LRI has developed through its research numerous quality-assured databases and key tools freely available to all. The aim of this initiative is to freely provide European and national regulatory agencies, industry and academia with state-of-the-art and easy-to-use tools for better research, analysis and visualisation purposes for use in risk assessment and toxicity testing of chemicals, and in preparation of regulatory filings such as REACH, GHS etc.

These tools are either databases or predictive models that reduce testing and provide significant financial and resources savings to users. The LRI has invested around 3.3 million euros on research projects for the development of the Toolbox, while the use of the tools is expected to allow the users to save several tens of million euros, particularly through animal use savings.

The LRI Toolbox is a repository of 14 tools subdivided into the 3 following categories:

Human health databases

CEMAS database

Cefic Exposure MAnagement System

FeDTex

Fertility and Developmental Toxicity in Experimental Animals

RepDose

Relational database on subacute to chronic toxicity

 

Human health models

AMBIT

Cheminformatics Data Management System

ART

Advanced REACH Tool

BiotS

Biotransformation Susceptibility software

Busy

Bayesian Uncertainty System

IndusChemFate

OLIMPIC CRAFT

PBPK / MEGen

Physiologically-Based Pharmacokinetic Modelling / Model Equation Generator

 

Environmental models

ADEPT

Atmospheric DEPosition and Transport model

BCF database

GEMCO

Generic Estuary Model for COntaminants

GREAT-ER

Geography-referenced Regional Exposure Assessment Tool for European Rivers

TERRACE

Terrestrial Runoff Modelling for Risk Assessment of Chemical Exposure

 

The LRI Toolbox will be featured at the 12th Annual Cefic-LRI Workshop on 17-18 November in Brussels, at the ECOPA/IPAM Conference on 26 November in Milan and at the EPAA 2010 Annual Conference on 30 November in Brussels. Click here to download the flyer of the LRI Toolbox.